To explore the role of WAVE3 in tumorigenicity of ovarian cancer cells in vivo, SKOV3/shRNA-WAVE3 cells that expressed low level WAVE3 stably and A2780/pcDNA3.1-WAVE3 cells which is WAVE3 high-expression, together with their primary cells were delivered as cell suspensions and injected subcutaneously into the right armpit of BALB/c athymic nude mice. Here, WASF3 is linked to ovarian cancer.