We previously demonstrated that cSBL induces apoptosis in H28 (sarcomatoid histological type) as well as MESO-1 and MESO-4 (epithelioid type) cells, and that the synergistic anti-tumor effect of cSBL + TRAIL in H28 cells was mediated by an increase in apoptosis [25]. The gene discussed is TNFSF10; the disease is neoplasm.