Presence of activated microglia cells has been demonstrated in the surroundings of amyloid plaques and hyperphosphorylated tau in Alzheimer’s disease (AD) and alpha-synuclein fibrils in Parkinson disease (PD) [4], thus suggesting a biochemical link between the accumulating toxic proteins and microglia activation in neurodegenerative diseases. The gene discussed is MAPT; the disease is Alzheimer disease.