LDLR and steatosis: mRNA expression of lipogenic transcription factor Strebp‐1c was significantly decreased in livers from both, LDLR+/+ and LDLR−/− fed a high fat sugar diet with supplementary Vitamin D3 compared to their controls (supplementary Fig S1), demonstrating transcriptional adaptation to the presence of Vitamin D3 in avoidance of developing steatosis.