NFKB1 and glioblastoma: In particular, overexpression of miR-21 protected the glioblastoma U87MG cell line against temozolomide-induced apoptosis [92], while the repression of miR-21 expression sensitizes glioblastoma cells to teniposide treatment via inhibition of nuclear factor kappa-B (NF-κB) signaling [93].