During the past two decades, extensive studies have focused on the surrogate MRI characters of tumor grade (defined by histopathology) and genetic subtype (defined by 1p/19q co-deletion or IDH mutation) of CNS tumors [19, 23, 24, 27, 28], whereas these two genic alterations act as diagnostic markers rather than grouping factors for ODs [12]. This evidence concerns the gene IDH1 and neoplasm.