In recent years, GWAS have revealed a series of new susceptibility genes for AD, including ABCA7, BIN1, CR1, CD2AP, CD33, CASS4, CELF1, CLU, EPHA1, FERMT2, HLADRB5/HLA-DRB1, INPP5D, MS4A6A, MEF2C, NME8, PICALM, PTK2B, SLC24A4/RIN3, SORL1, TREM2, and ZCWPW1 [9, 10, 13, 75–82]. The gene discussed is TREM2; the disease is Alzheimer disease.