The alanyl (membrane) aminopeptidase (ANPEP) gene resides in a locus on chromosome 15 containing variants associated with T2D in South Asian individuals (Kooner et al., 2011) and its expression levels are furthermore associated with the T2D associated SNP rs560887 (G6PC2 locus on chromosome 2), thus, representing a trans-eQTL (Taneera et al., 2012). Here, ANPEP is linked to type 2 diabetes mellitus.