The islet expression of Family with sequence similarity 105, member A (FAM105A) and PDZ and LIM domain 4 (PDLIM4) was associated with both T2D (Marselli et al., 2010; Taneera et al., 2012) and hyperglycemia (Taneera et al., 2012). The gene discussed is OTULINL; the disease is Hyperglycemia.