Treatment of tumor-bearing mice with Salmonellae carrying pTGFα-PE38 or pSEC-TGFα-PE38, followed by induction with L-arabinose (at 3.5 dpi and at 7.5 dpi), led to significant retardation in the growth of all the tumor tissues except that of SW620: no discernable change was observed. Here, TGFA is linked to neoplasm.