According to the molecular profiles of IBC, some studies confirmed that tumors from IBC activated NF-κB to accumulate pro-inflammatory cytokines [18], lost Wnt-inducible signaling protein 3 to activate insulin-like growth factor signaling [19], upregulated the Rho C GTPase gene [20] and so on. This evidence concerns the gene NFKB1 and inflammatory breast carcinoma.