Of these 15 regulators, 13 have already been described in the context of melanoma (e.g. ZBTB7A (63), MITF (64) and ATF2 (65,66)) and twelve are known to be involved in metastasis or tumor progression in melanoma (e.g. GATA3 (67)) or other cancer types (e.g. CEBPA (68)). This evidence concerns the gene ZBTB7A and melanoma.