Of these 15 regulators, 13 have already been described in the context of melanoma (e.g. ZBTB7A (63), MITF (64) and ATF2 (65,66)) and twelve are known to be involved in metastasis or tumor progression in melanoma (e.g. GATA3 (67)) or other cancer types (e.g. CEBPA (68)). Here, GATA3 is linked to melanoma.