UBE2I and cancer: In particular, miR-103a-3p is reported to be involved in different biological functions, such as cell cycle progression [25] and cell differentiation [26]; while mi-R-30e-3p, a member of the miR 30 family, is involved in the cell growth, apoptosis related to cancer development as it might negatively regulate the expression of Ubc9, a key regulator of the stimulation-mediated cell growth pathway and cancer development [27].