In silico experimentation pointed out that an increase of prothrombin conversion in liver cirrhosis patients to a physiological level will provoke a procoagulant state in CP-B and CP-C patients (ETP 300% of baseline on average), whereas the normalization of AT levels will cause a severe reduction of the ETP (half of all patients would have an ETP lower than 75% of normal). The gene discussed is F2; the disease is cirrhosis of liver.