In contrast to the lack of association between CNV of the tested FCGR genes and development of Stages I-III of SA in our patients, a decreased CN of FCGR3A gene has been revealed in Taiwanese patients with RA and SLE, although also an increased CN was shown to be a risk factor for the disease development in the same patients with SLE [31]. Here, FCGR2A is linked to systemic lupus erythematosus.