Furthermore, in the light of the previously reported polymorphism of FCGR2A, FCGR2C and FCGR3A genes in our patients with SA, as well as the lack of association between CNV of FCGR2A, FCGR2B, FCGR2C, FCGR3A and FCGR3B genes in Stages I, II and III of SA, and in all patients with SA analyzed together, polymorphism of FCGR genes seems to have a greater impact on genetic predisposition to develop sarcoidosis than copy number variation of these genes. This evidence concerns the gene FCGR3A and sarcoidosis.