OSM and neoplasm: Other key factors associated with immune function, with a lower gene expression in MLL-LNs vs. AT1-LNs, were Osm–shown to induce formation of high endothelial venules and thereby affect recruitment of immune cells to the LN [91], and Tnfs11 –regulates dendritic cell survival and LN formation [92] and enhance T cell response to tumor antigens [93].