Genes with higher expression in MLL- vs. AT1-tumors whose gene products potentially could be tumor-derived secreted factors were Cxcl12 (5-fold increased), Kitlg (3-fold), Osm (2-fold), S100a9 (10-fold), and Tgfa (2-fold), and genes with higher expression in AT1-tumors than in MLL-tumors were Adamts12 (8-fold), Fbn1 (3-fold) and Cr1l (2-fold) (Fig 7B). This evidence concerns the gene KMT2A and neoplasm.