ROMO1 and metastatic malignant neoplasm in the lymph nodes: By multivariate analysis, lymph node metastasis (HR: 3.733, 95% CI: 1.520–9.169), higher LNR (HR: 2.329, 95% CI: 0.997–5.441), and higher Romo1 expression (HR: 3.198, 95% CI: 1.376–7.436) were significantly related to poorer OS.