Contrary to our expectations, although Dip G is capable of increasing STAT1 mRNA expression in AML cells, there were no significant changes in total STAT1 and p-STAT1 (Ser727) protein levels in the whole-cell lysates of Dip G-treated HL-60 cells except for a slight decrease in the protein levels of p-STAT1 (Tyr701) (Figure 4a). The gene discussed is STAT1; the disease is acute myeloid leukemia.