On the other hand, Magalhães et al. [26] showed that in Chagas patients with cardiac form the total lymphocytes and the Th17 cells presented a low expression of IL-17A in comparison to the patients with the indeterminate form and control group, and the analysis of correlation between IL-17A and the cardiac function showed that the high expression of this cytokine was associated with a better clinical outcome in the human CD, according to values of the ejection fraction and left ventricular diastolic diameter, indicating a protective role against the severity of CCC. The gene discussed is IL17A; the disease is Cowden disease.