VEGFA and choroidal neovascularization: Also, the minimum bevacizumab concentration (500 ng/ml) to block VEGF-A effects is observed up to 48 days and the concentration above the half maximal inhibitory concentration (22 ng/ml) could be maintained for approximately 78 days after 1.25 mg intravitreal injection in eyes with choroidal neovascularization [34].