BDNF and myeloid sarcoma: Reduced local expression of BDNF mRNA in adult MS (Roceri et al., 2004), LN (Roth et al., 2009), and PS offspring due to increased Bdnf DNA methylation [associated with an increase in DNA methyltransferase 1 (DNMT1) expression; Roth et al., 2009; Dong et al., 2015], may relate to these changes.