FPR1 and acute respiratory distress syndrome: Despite evidence of cellular crosstalk with innate inflammatory cells, the exact dynamics and key contributors to intrinsic alveolar epithelial cell dysfunction in the pathogenesis of ARDS remain poorly understood.1 The role of FPR1 in colonic epithelial homeostasis32 and formylated peptides in bronchial epithelial migration and contraction36, 37 and systemic vascular tone38 has recently been described.