Parvalbumin (PA) is another Ca2+-binding protein that is selectively expressed in a class of GABAergic interneurons of the dorsolateral prefrontal cortex (Benes and Berretta, 2001; Kretsinger and Nockolds, 1973), a region also affected in PD patients (Kikuchi et al., 2001). The gene discussed is PVALB; the disease is Parkinson disease.