In addition to FGFR3 and FGFR1, the sequencing panel incorporated genes with reported alterations in gliomas, including IDH1, IDH2, TP53, ATRX, CIC, CDKN2A, RB1, RELA, and BRAF (Additional file 1: Table S1). This evidence concerns the gene CDKN2A and central nervous system cancer.