Although miR-511-3p is upregulated in M2 macrophages, experimentally induced upregulation of miR-511-3p attenuates the tumor-promoting functions of M2-like TAMs by targeting Rock2, which promotes the M2-like phenotype of macrophages by enhancing expression and secretion of ECM that facilitate tumor growth and vascularization [88]. The gene discussed is ROCK2; the disease is neoplasm.