CCL2 and dry age related macular degeneration: Interestingly, the decreased Ccl2 (0.71 fold, P = 0.046) and Ccr2 (0.804 fold, P < 0.0001) in the aged 5XFAD mice is reminiscent of the Ccl2 or Ccr2 deficient mouse model of dry AMD (Figure 6C) [12].