The remaining eight are known fusion transcripts (e.g. TMPRSS2-ERG, C9orf163-SEC16A, SMG5-TMEM79, and KLK4-KLK3) [5, 21, 22], of which TMPRSS2-ERG is the most common, and was found to be positive in 19 (45%) of the 44 primary tumor samples (Table 1). The gene discussed is KLK4; the disease is neoplasm.