In the multivariate Cox regression analysis of grade II and III gliomas, both IDH mutation (p < 0.001) and positive SSTR2A (p = 0.013) remained independent factors that were significantly associated with longer overall survival, after adjustment for age, preoperative Karnofsky Performance Scale (KPS), and resection type (Table 3). This evidence concerns the gene IDH1 and central nervous system cancer.