However, both JMJD2A plus P21WAF1/Cip1 and JMJD2A plus Pim1RNAi did significantly not alter the colony formation rate of liver cancer cells (32.63 ± 8.66%, 30.64 ± 5.01% vs 29.73 ± 7.44%, P = 0.2027 > 0.05, 0.4544 > 0.05, respectively) (Figure 8D). This evidence concerns the gene KDM4A and liver cancer.