Therefore, a case–control study was published in an effort to describe the unparalleled strength of this modality in comparison to other strategies used to prevent OHSS.6 The use of intravenous albumin around the time of oocyte retrieval was also suggested as a major intervention to prevent OHSS; however, our experience, as well as that of others, led to abandonment of this approach.7 This evidence concerns the gene ALB and ovarian hyperstimulation syndrome.