Furthermore, analysis of a glioma genome-wide association dataset identified a possible contribution by a TAS2R8 single nucleotide polymorphism to glioma susceptibility [63], while TAS2R10 has been found to be up-regulated in patients with Parkinson disease and to have a role in the treatment of asthma in rats [64, 65]. This evidence concerns the gene TAS2R8 and central nervous system cancer.