The AE-IIP patients had a reduced P/F ratio of 206 ± 16 mmHg, as well as elevated KL-6, surfactant protein (SP)-A, and SP-D levels of 1524 ± 127 U/mL (reference < 500 U/mL), 119 ± 7 ng/mL (reference < 43.8 ng/mL), and 344 ± 53 ng/mL (reference < 110 ng/mL), respectively (Table 1). This evidence concerns the gene MUC1 and acrodermatitis enteropathica.