AKT3 and bipolar disorder: Genetic variation in the AKT3 locus (chr1:243503719–244002945) is a top GWAS signal in schizophrenia [5,8] and pathway analysis identified 50 single nucleotide polymorphisms (SNPs) within the AKT3 gene that contribute to four of the top pathways associated with risk for schizophrenia and bipolar disorder [6].