That the DMBA/acetone treated TCF7L1-induced mice developed tumors at a similar rate to the DMBA/TPA treated control mice (Figure 2E–J) suggests that TCF7L1 can act as a tumor promoter, since its expression was able to substitute for pro-inflammatory TPA application in the DMBA/TPA chemical carcinogenesis protocol. Here, TCF7L1 is linked to neoplasm.