MSH6 and colorectal carcinoma: The median age at CRC diagnosis of patients with the MSH6 p.Leu585Pro mutation was 60 (Q1 51, Q3 73; range 41–75) and the median age of patients with the PMS2 p.Pro246Cysfs*3 mutation was 60.5 (Q1 50.5, Q3 70; range 31–86).