Of note, the first patient obtaining PR previously reported (Kochenderfer et al., 2010) developed progressive CD19+ lymphoma 32 weeks after his first infusion of anti-CD19 28ζ CAR-T cells, whereas B cell dysplasia lasted 39 weeks and 36 weeks after the first CAR-T cell infusion in the peripheral blood (PB) and BM, respectively. This evidence concerns the gene CD19 and lymphoma.