FOLH1 and metastatic prostate carcinoma: PSMA-targeted CAR-T cells for patients with castrate metastatic prostate cancer (CMPC) was tested in a dose escalation study performed at MSKCC (NCT01140373), and early experiences in the first three patients who received dose level 1 (1 × 107 CAR+ T cells/kg) following 300 mg/m2 of Cy one day were presented at ASCO 2012 by Slovin et al. No toxicities occurred, and two of three treated patients had SD for longer than 6 months (Slovin et al., 2012).