This group also reported the result of a trial (NCT01087294) to evaluate donor-derived CD19-targeted 28ζ CAR-T cells without prior lymphodepleting chemotherapy for patients with B-NHL or CLL in whom tumor lesions persisted after allo-HSCT and standard donor lymphocyte infusions (DLIs) (Kochenderfer et al., 2013). The gene discussed is CD19; the disease is B-cell chronic lymphocytic leukemia.