Our previous studies showed there is only PlA1/A1 allele of GP IIIa expressed in 251 Chinese patients, while the human platelet antigen- (HPA-) 3 polymorphism (rs5911) in GP IIb is proved to be an independent risk factor of CAD with the mutation of 31% [8, 9]. The gene discussed is ITGB3; the disease is coronary artery disorder.