ITGA2B and coronary artery disorder: Plasma hs-CRP level also increased significantly in AR and ASR group, which was in accordance with the results from Larsen et al. [14], who reported that increased levels of hs-CRP were associated with augmented platelet reactivity in Denmark stable high-risk CAD patients receiving aspirin as mono antiplatelet therapy, but no genetic variations in COX-1 or GPIIb were found to be related to hs-CRP level.