IRF2 and colorectal carcinoma: Results of Log-rank test indicated that patients with CRC of high IRF-2 expression tend to have worse overall survival with a mean overall survival of 39.2 months (95% CI 35.8 to 42.6), while those with low IRF-2 expression tend to have better overall survival with a mean overall survival time of 45.2 months (95% CI 43.0 to 47.2) (P = 0.006) (Figure 2A).