MCM7 and prostate carcinoma: Moreover, numerous studies have demonstrated that MCM7 is a pivotal component of the DNA replication initiation complex in Xenopus and yeast [9–12]; it also serves as a proliferation marker and is correlated with tumorigenesis in several human malignancies, including prostate cancer [13], ovarian cancer [14], endometrial carcinoma [15], oral squamous cell carcinoma [16], esophageal adenocarcinoma [17], colorectal adenocarcinoma [18], and glioblastoma [19].