EGFR and hepatocellular carcinoma: It has been reported previously that GE11 is able to bind EGFR especially those of human hepatoma cell line SMMC-7721 [11], human non-small cell lung carcinoma cell line H1299 [12], human glioblastoma astrocytoma U87-MG [32], non-small cell lung cancer A549 [33], human ovarian adenocarcinoma SKOV3 [14, 16] and breast cancer HCC70 cells [34].