The results demonstrate that ARC is stongly expressed in all RCC cell lines, whereas expression of the antiapoptotic Bcl-2 famlily members (Bcl-2, Bcl-xl, Bcl-w and Mcl-1) differs between the cell lines, with a strong expression of Bcl-xl in clearCa-3, −5, −7, and −11 as well as Mcl-1 in clearCa-11 as compared to the other RCC cell lines and a weak expression of Bcl-w in all tested cell lines as well as Bcl-2 and Mcl-1 in clearCa-3 and clearCa-12, respectively (Fig. 3a). Here, ARC is linked to renal cell carcinoma.