NFKB1 and prostate adenocarcinoma: Dilshara et al. [41] determined that mangiferin substantially lowered TNFα-induced MMP-9 activity, decreased nuclear factor-κB (NF-κB) activity, and suppressed nuclear translocation of the NF-κB subunits p65 and p50 in androgen-sensitive human prostate adenocarcinoma cells.