LAPTM5 and acute promyelocytic leukemia: As shown in Fig 3B, LAPTM5 mRNA was detected in human peripheral T cells and immature malignant cells in the myeloid lineage such as chronic myelogenous leukemia K562 cells, promyelocytic leukemia HL-60 cells, promonocytic leukemia U937 cells, and acute monocytic leukemia THP-1 cells.