As compared to those of the control group, the results of RT-qPCR also indicated a significant increase in the mRNA levels of IL-8, IL-23, TNF-α and ICAM-1 in the skin lesions of imiquimod-induced psoriasis-like mice from the model groups, however, their mRNA levels are significantly decreased in the PAMs treated mice. This evidence concerns the gene ICAM1 and psoriasis.