In contrast, following the onset of GvHD after 26 days, significant differences in favor of CD4+ cells were detectable in PEI treated animals (pvs.control = 0.022, pvs.Ibafect = 0.023, pvs. PEI, day 12 = 0.03; Ncontrol, day 26 = 6, NIbafect, day 26 = 2, NPEI, day 12 = 11, NPEI, day 26 = 10), but not in untreated controls or upon Ibafect treatment. The gene discussed is CD4; the disease is graft versus host disease.