While 46% of HIV patients in our study had nadir CD4+ T cell counts of <200 cells/μL, we observed no associations between nadir CD4+ T cell count and IgG1+ or IgG2+ ASCs, though there were weak correlations between nadir CD4+ T cell count and fold change in serum IgG2 antibodies to PcP 4 and 9V in ART-treated HIV patients (S7C Table). Here, CD4 is linked to pneumocystosis.