GFRA4 and cancer: There are seven transcripts (e.g. SGK1; GDNF receptor alpha-4, GFRA4; thymosin beta 4, TMSB4) (Supplementary file 8) with higher expression in salamander cells with algal symbionts that are linked to cell survival in different physiological contexts including cancer cell survival and proliferation, and neuronal survival during development (Lang et al., 2010; Enokido et al., 1998; Bock-Marquette et al., 2004).