In addition to the key role of these PLIs for snake physiology, the identification and characterization of PLIs are of great interest for biotechnological purposes, especially those called MIPs (myotoxin inhibitor toxin), which target specifically basic Asp49- and Lys49-PLA2s, responsible for local myonecrosis, one of the most serious consequences of B. jararaca envenoming (Campos et al., 2016; Mora-Obando et al., 2014; Santoro et al., 2008). The gene discussed is PLA2G2A; the disease is gas gangrene.