In general, increased intratumoral morphological diversitycorrelated with considerable chemoresistance and a high metastasis rate of BC.We found variable expressions of epithelial (EPCAM andCDH1) and mesenchymal (ITGA5,ITGB5, CDH2, CDH11,TGFb2, ZEB1, MMP2,DCN, MST1R) markers and, thus, different EMTmanifestations in different morphological structures. The gene discussed is ITGB5; the disease is breast cancer.