MPDZ and Hydrocephalus: Genetic testing using a gene panel for non-syndromic congenital hydrocephalus led us to identify a second MPDZ homozygous pathogenic variant in a foetus born to consanguineous Senegalese parents (Family 1; Fig. 1) who displayed atresia/forking of the aqueduct of Sylvius, suggesting that the specific phenotype of hydrocephalus due to atresia/forking of the aqueduct of Sylvius results from MPDZ mutations.