Similar to the MCF10A CDH1(−/−) mutant cells, c.1380delA CDH1 SB.mhdgc-1 gastric cancer cells showed altered gene expression of genes involved in cellular component organization, cytoskeletal organization, and cell adhesion (Additional file 4: Figure S2), including microtubule nucleation involving genes like TUBB2 [28]. The gene discussed is CDH1; the disease is gastric cancer.