CDH1 and Familial gastric cancer: To compare the loss of CDH1 due to germline mutations in gastric cancer cells derived from a HDGC patient to sporadic gastric cancer cells, we performed genome-wide microarray profiling in c.1380delA CDH1 SB.mhdgc-1 and 7 sporadic gastric cancer cell lines using the Illumina HumanHT-12 v4 platform.