CDH1 and Familial gastric cancer: To develop new therapeutic strategies for HDGC patients, we compared drug sensitivity profiles derived from a dose response quantitative high throughput drug (qHTS) screens of 1912 oncology compounds between c.del1380A CDH1 gastric cancer cells derived from a HDGC patient, and wild type CDH1 gastric cancer cells derived from a sporadic gastric cancer patient.