Flow cytometry analysis of cell death measured by labeling DNA breaks with FITC-dUTP confirmed increased fraction of BrU positive cells in mitoxantrone, etoposide, and PI-103-treated hereditary c.1380delA CDH1 mutant SB.mhdgc-1 gastric cancer cells showed increased cell death compared to sporadic gastric cancer cells (Fig. 5b). This evidence concerns the gene CDH1 and gastric cancer.