To examine if detected transcriptomic perturbations in cytoskeletal regulation in hereditary c.1380delA SB.mhdgc-1 cells measured by Gene Ontology (GO) cellular process analysis and Analyze Networks (AN) algorithm might result in altered adhesion function, we compared next the ability of c.1380delA SB.mhdgc.-1 gastric cancer to SB.msgc-1 cells to adhere on regular non-treated tissue culture flasks, and then examined rescue by repeating adhesion experiments on plates coated with extracellular matrix molecules including collagen I, fibronectin, and laminin. This evidence concerns the gene FN1 and gastric cancer.