Or, eleven percent of the 205 primary gastric adenocarcinoma, examined as part of the TCGA effort, harbored somatic mutations in the CDH1 gene, which occurred nearly exclusively in the genomically stable (GS) gastric cancer subtype (37% of GS cases) which, by far, comprised of the largest number of cancers with diffuse histology [25]. This evidence concerns the gene CDH1 and gastric adenocarcinoma.